Sulbutiamine

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GRAND WUYAO (JIANGSU) PHARMACEUTICAL CO., LTD

Business Type:Manufacturer

Country/Region:China

Ddu Verified

HOT Rank

6/10

Product Information

  • Transport Package:1KG/bag
  • Specification:In-house
  • Country of Origin:China

Description

1. Basic Identification
  • English Name: Sultiamine API
  • CAS Number: 130-06-3
  • Molecular Formula: C₂₀H₃₄N₄O₄S₂
  • Molecular Weight: 474.64 g/mol


2. Physical Properties
  • Appearance: White to off-white crystalline powder
  • Solubility: Soluble in water and ethanol; slightly soluble in chloroform
  • Storage: Store at room temperature (20–25°C), protected from light and moisture in airtight containers


3. Pharmaceutical Uses
  • Indications: Used as a vitamin B1 (thiamine) derivative for treating neurological disorders, diabetic neuropathy, and beriberi.
  • Mechanism: Converted to thiamine diphosphate in vivo, enhancing thiamine absorption and utilization for neuronal function.
  • Route: Oral administration (tablets/capsules) or intramuscular injection.


4. Quality Standards
  • Pharmacopoeias: USP, EP, ChP (where applicable)
  • Key Specs:
    • Purity ≥98.5% (HPLC)
    • Related substances ≤1.0% (individual impurity limits)
    • Residual solvents compliant with ICH guidelines


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